Household survey 住戶調查

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病毒性肝炎的流行病學研究

病毒性肝炎仍然是香港主要的公共衛生問題。研究團隊希望透過本流行病學研究,掌握病毒性肝炎在本港人口中的分佈及風險因素,並為制訂防控肝炎的公共衛生政策提供最新的資料。

肝炎檢測是獲得適切的防治服務的先決條件,尤其是當大部分肝炎患者並不清楚他們的感染情況。透過檢測及早管理肝炎,不但可維持個人健康,並能有效降低肝炎在社群間的潛在傳播風險及減少其公共衛生負擔。

An epidemiological study about viral hepatitis

Viral hepatitis remains a public health threat in Hong Kong. The major interest of this epidemiological study would be the distribution and determinants of viral hepatitis in Hong Kong population. This study is expected to provide updated information for public health policy formulation by identifying risk factors and targets for disease control and prevention.

As most people with hepatitis are unaware of their infection status, testing for viral hepatitis is the gateway for access to appropriate prevention and treatment services. Getting tested for prompt disease management could not only maintain the health of an individual, but also reduce its public health burden by minimizing the transmission potential in the community.

 

研究設計

這是一份全港性的住戶調查,主要是關於兩類現時能靠疫苗預防的病毒性肝炎,包括甲型肝炎及乙型肝炎。

被選中的住戶中的所有家庭成員均可參與本研究。參加者需完成一份問卷調查,並提供血液樣本予研究團隊作肝炎病毒抗原及抗體測試。參加者可選擇親臨研究中心抽血,或自行使用測試工具採集乾血點予研究團隊。

Study design

This is a territory-wide cross-sectional household survey on two types of vaccine-preventable viral hepatitis, namely hepatitis A and hepatitis B.

All members in selected households are invited to complete a questionnaire and submit blood samples to the Research Team for serology testing. Blood samples could be taken in person at the research centre or by submitting self-collected dried blood spot testing kits.

 

研究目的

本研究旨在評估甲型及乙型肝炎在香港人口中的感染情況及傳播風險,從而提升公共衛生組織應對病毒性肝炎的能力。

本研究有三項目標:

  1. 估算甲型及乙型肝炎在香港人口中的流行情況
  2. 分析與病毒性肝炎相關的風險因素、疫苗接種記錄及接種意向
  3. 透過建立數學模型,評估甲型及乙型肝炎在香港人口中的傳播風險

香港中文大學 – 新界東醫院聯網臨床研究倫理聯席委員會被授權在有需要時審視個人資料藉以評估研究倫理(參考編號:2017.697)。如果你有更多關於臨床研究倫理相關問題,請與該委員會聯繫 (電郵 crec@cuhk.edu.hk 或 致電 3505 3935) 。

Aim and objectives

This study aims to enhance the capability of public health authorities by assessing the susceptibility and transmission potential of hepatitis A and B in the general population in Hong Kong.

The objectives are to:

  1. determine the population-level seroprevalence of hepatitis A and B in Hong Kong,
  2. examine the risk factors, vaccination history and intention to get vaccinated against viral hepatitis, and
  3. assess the transmission potential of hepatitis A and B in the general population by mathematical modelling.

The Joint Chinese University of Hong Kong – New Territories East Cluster Clinical Research Ethics Committee has approved this study (Ref. No.: 2017.697) and is authorized to access the participants' records related to the study for ethics review purpose. For enquiry regarding clinical research ethics, please contact the Committee at crec@cuhk.edu.hk and phone at 3505 3935.

 

 

參加資格

參加者須:

  1. 為受邀請家庭住戶中的成員
  2. 通常在港居住
  3. 懂得中文或英文
  4. 並非外籍家庭傭工
  5. 獲得合法監護人的同意(適用於未滿18歲的家庭成員)

Eligibility criteria

To join the study, you must:

  1. be a member in the invited domestic household;
  2. normally reside in Hong Kong;
  3. able to understand written Chinese or English;
  4. not be a foreign domestic helper; and
  5. have informed consent from your legal guardian, if you are aged below 18

 

研究流程 Flow chart of the study

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Blood sampling for laboratory testing

Blood samples shall be obtained either by venesection or collected dried blood spots. The following virus and immunity markers will be tested:

  • Anti-HAV
  • HBsAg
  • Anti-HBs
  • Anti-HBc

Clinical interpretation of each marker can be found here.

血液樣本測試

經抽血或乾血點所抽取的血液樣本將會就以下四種感染指標進行測試:

  • 甲型肝炎抗體
  • 乙型肝炎表面抗原
  • 乙型肝炎表面抗體
  • 乙型肝炎核心抗體

想了解各指標的臨床意義,請按此處

 

想了解更多或參與研究?
Want to know more or participate in the study?

若你對本研究有任何疑問,歡迎以電郵聯絡 info@hepfree.hk
For further information, please contact info@hepfree.hk.

本研究只接受受邀請的住戶中的家庭成員參與,項目負責人保留最終決定權。
This study only accepts participants from invited domestic households. The principal investigator's decision is final.